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Preheat oven to 450 degrees. line baking sheet with foil and set aside. Place the mushrooms in a food processor and pulse until they are very finely chopped; scrape them into a large mixing bowl. Add the garlic cloves to the food processor and pulse until they are finely chopped. Add the egg substitute and 1 tbsp of the ketchup, and puree until the garlic is smooth. Scrape the garlic mixture into the bowl containing the mushrooms. Add beef, parsley and panko to the bowl. Add salt and pepper to taste. Using your hands gently mix the ingredients until they are just combined. On the prepared baking sheet form the meat mixture into 8x4x1 1/2" loaf. Brush the remaining ketchup over the loaf. Bake until the meatloaf is cooked through, 18-20 minutes. Allow meatloaf to rest for 5 minutes before slicing.
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